Insulin resistance: Difference between revisions
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In [[medicine]], '''insulin resistance''' is "diminished effectiveness of [[insulin]] in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent hyperglycemia or ketosis. Tt can be caused by the presence of insulin antibodies or the abnormalities in insulin receptors (receptor, insulin) on target cell surfaces. It is often associated with [[obesity]]; [[diabetic ketoacidosis]]; [[infection]]; and certain rare conditions."<ref>{{MeSH}}</ref> | In [[medicine]], '''insulin resistance''' is "diminished effectiveness of [[insulin]] in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent hyperglycemia or ketosis. Tt can be caused by the presence of insulin antibodies or the abnormalities in insulin receptors (receptor, insulin) on target cell surfaces. It is often associated with [[obesity]]; [[diabetic ketoacidosis]]; [[infection]]; and certain rare conditions."<ref>{{MeSH}}</ref> | ||
[[Insulin resistance]] (HOMA-IR) can be measured by:<ref name="pmid3899825">{{cite journal |author=Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC |title=Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man |journal=Diabetologia |volume=28 | [[Insulin resistance]] (HOMA-IR) can be measured by:<ref name="pmid3899825">{{cite journal |author=Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC |title=Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man |journal=Diabetologia |volume=28 |pages=412–9 |year=1985 |pmid=3899825 |doi= |url= |issn=}}</ref> | ||
:<math>\text{HOMA-IR} = \frac{\text{fasting plasma glucose} * \text{fasting insulin}}{22.5}</math> | :<math>\text{HOMA-IR} = \frac{\text{fasting plasma glucose} * \text{fasting insulin}}{22.5}</math> | ||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 04:19, 30 July 2009
In medicine, insulin resistance is "diminished effectiveness of insulin in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent hyperglycemia or ketosis. Tt can be caused by the presence of insulin antibodies or the abnormalities in insulin receptors (receptor, insulin) on target cell surfaces. It is often associated with obesity; diabetic ketoacidosis; infection; and certain rare conditions."[1]
Insulin resistance (HOMA-IR) can be measured by:[2]
References
- ↑ Anonymous (2024), Insulin resistance (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985). "Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man". Diabetologia 28: 412–9. PMID 3899825. [e]