G-protein-coupled receptor/Related Articles

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• Adrenergic receptor [r]: Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. ^[e]
• Cell surface receptor [r]: Proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell. ^[e]
• Drug discovery [r]: Process by which pharmaceuticals are discovered and/or designed. ^[e]
• G-protein-coupled receptor kinase [r]: A family of protein kinases which regulate the activity of G protein-coupled receptors (GPCRs) by phosphorylating their intracellular domains after their associated G proteins have been released and activated. ^[e]
• Oxytocin [r]: A mammalian hormone that is secreted into the bloodstream from the posterior pituitary gland, and which is also released into the brain where it has effects on social behaviors. ^[e]
• Protein kinase [r]: A family of enzymes that catalyze the conversion of adenosine triphosphate and a protein to adenosine diphosphate and a phosphoprotein. ^[e]