Biological networks/Bibliography: Difference between revisions
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* Bray D. (2003) [http://dx.doi.org/10.1126/science.1089118 Molecular Networks: The Top-Down View.] ''Science'' 301:1864-1865. | * Bray D. (2003) [http://dx.doi.org/10.1126/science.1089118 Molecular Networks: The Top-Down View.] ''Science'' 301:1864-1865. | ||
**'''Excerpt:''' Everything in a living cell is, of course, connected to everything else, and interactions between macromolecules through multiple noncovalent bonds are the very fabric of life. It is therefore an attractive notion that, by taking a top-down view of protein-protein interactions, enzymatic pathways, signaling pathways, and gene regulatory pathways, we will gain a better perspective of how they work. | **'''Excerpt:''' Everything in a living cell is, of course, connected to everything else, and interactions between macromolecules through multiple noncovalent bonds are the very fabric of life. It is therefore an attractive notion that, by taking a top-down view of protein-protein interactions, enzymatic pathways, signaling pathways, and gene regulatory pathways, we will gain a better perspective of how they work. | ||
* Alon U. (2003) [http://dx.doi.org/10.1126/science.1089072 Biological Networks: The Tinkerer as an Engineer.] Science'' 301:1866-1867. | |||
** '''Excerpt:''' This viewpoint [article] comments on recent advances in understanding the design principles of biological networks. It highlights the surprising discovery of "good-engineering" principles in biochemical circuitry that evolved by random tinkering. | |||
Revision as of 23:19, 12 January 2010
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- Bray D. (2003) Molecular Networks: The Top-Down View. Science 301:1864-1865.
- Excerpt: Everything in a living cell is, of course, connected to everything else, and interactions between macromolecules through multiple noncovalent bonds are the very fabric of life. It is therefore an attractive notion that, by taking a top-down view of protein-protein interactions, enzymatic pathways, signaling pathways, and gene regulatory pathways, we will gain a better perspective of how they work.
- Alon U. (2003) Biological Networks: The Tinkerer as an Engineer. Science 301:1866-1867.
- Excerpt: This viewpoint [article] comments on recent advances in understanding the design principles of biological networks. It highlights the surprising discovery of "good-engineering" principles in biochemical circuitry that evolved by random tinkering.