Glucocorticoid receptor: Difference between revisions
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'''Glucocorticoid receptors''' are intracellular proteins to which drugs of the [[Corticosteroid#Glucocorticoids|glucocorticoid]] class bind and cause physiologic affects. They are related to [[ | {{subpages}} | ||
'''Glucocorticoid receptors''' are intracellular proteins to which drugs of the [[Corticosteroid#Glucocorticoids|glucocorticoid]] class bind and cause physiologic affects. They are related to [[mineralocorticoid receptor]]s and less so to [[androgen receptor]]s and [[estrogen receptor]]s. | |||
[[Corticosteroid#Glucocorticoids|Glucocorticoid]]s were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important natural example.<ref>National Library of Medicine, Medical Subject Headings (MeSH)</ref> A wide range of synthetic drugs are in this category, and have a wide range of beneficial and side effects.<ref name=Bellanti>{{citation|title = Immunology III | author = Joseph A. Bellanti |publisher = W.B. Saunders | year = 1985}}, pp. 550-557</ref> | [[Corticosteroid#Glucocorticoids|Glucocorticoid]]s were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important natural example.<ref>National Library of Medicine, Medical Subject Headings (MeSH)</ref> A wide range of synthetic drugs are in this category, and have a wide range of beneficial and side effects.<ref name=Bellanti>{{citation|title = Immunology III | author = Joseph A. Bellanti |publisher = W.B. Saunders | year = 1985}}, pp. 550-557</ref> | ||
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Latest revision as of 12:01, 22 August 2024
Glucocorticoid receptors are intracellular proteins to which drugs of the glucocorticoid class bind and cause physiologic affects. They are related to mineralocorticoid receptors and less so to androgen receptors and estrogen receptors.
Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important natural example.[1] A wide range of synthetic drugs are in this category, and have a wide range of beneficial and side effects.[2]