Antineoplastic agent/Related Articles: Difference between revisions

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==Subtopics==
==Subtopics==
===Alkylating agents===
===Alkylating agents===
====Nitrogen mustard agents====
====[[Nitrogen mustards]]====
{{r|Cyclophosphamide}}
{{r|Cyclophosphamide}}
{{r|Chlorambucil}}
{{r|Chlorambucil}}
{{r|Melphalan}}
{{r|Melphalan}}
{{r|Mechlorethamine}}
{{r|Chlormethine}}
{{r|Chlormethine}}
{{r|Ifosfamide}}
{{r|Ifosfamide}}
{{r|Trofosfamide}}
{{r|Trofosfamide}}
{{r|Prednimustine}}
{{r|Prednimustine}}
====Alkyl sulfonates====
====Alkyl sulfonates====
{{r|busulfan}}
{{r|busulfan}}
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{{r|mannosulfan}}
{{r|mannosulfan}}
====Ethylene imines====
====Ethylene imines====
 
{{r|Thiotepa}}
ATC/DDD group L01AC.
{{r|Triaziquone}}
{{r|Carboquone}}
====Nitrosoureas====
====Nitrosoureas====
{{r|Nitrosourea}}
{{r|Carmustine}}
{{r|Lomustine}}
{{r|Semustine}}
{{r|Streptozocin}}
{{r|Fotemustine}}
{{r|Nimustine}}
{{r|Ranimustine}}


ATC/DDD group L01AD.
====Epoxides====
====Epoxides====
ATC/DDD group L01AG.
{{r|retoglucid}}
 
====Other alkylating agents====
====Other alkylating agents====
ATC/DDD group L01AX.
{{r|Dacarbazine}}
{{r|Mitobronitol}}
{{r|Pipobroman}}
{{r|Temozolomide}}
 
===Antimetabolites===
===Antimetabolites===
{{r|Antimetabolite}}
{{r|Antimetabolite}}
ATC/DDD group L01B.
====Folic acid analogues====
 
===Folic acid analogues===
{{r|Folic acid}}
{{r|Folic acid}}
{{r|Folic acid analog antimetabolite}}
{{r|Folic acid antagonist}}
ATC/DDD group L01BA. Examples include:
{{r|Methotrexate}}
 
{{r|Methotrexate}}is an inhibitor of tetrahydrofolate dehydrogenase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA."[5]
{{r|Raltitrexed}}
{{r|Raltitrexed}}
{{r|Pemetrexed }}
{{r|Pemetrexed }}


===Purine analogues===
====Purine analogues====
{{r|Purine analogue antimetabolite}}
{{r|Purine analogue antimetabolite}}
ATC/DDD group L01BB. Examples include:
{{r| mercaptopurine}}
{{r| mercaptopurine}} is an "antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
{{r|tioguanine}}
{{r|tioguanine}}
{{r|cladribine}}
{{r|cladribine}}
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{{r|clofarabine}}
{{r|clofarabine}}
{{r|nelarabine}}  
{{r|nelarabine}}  
====Pyrimidine analogues====
====Pyrimidine analogues====
{{r|Pyrimidine analog antimetabolite}}
{{r|Pyrimidine analog antimetabolite}}
ATC/DDD group L01BC. Examples include:
{{r|cytarabine}}
{{r|cytarabine}}"pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties."[7]
{{r|fluorouracil}}
{{r|fluorouracil
{{r|tegafur}}
{{r|tegafur
{{r|carmofur}}
{{r|carmofur
{{r|gemcitabine}}
{{r|gemcitabine
{{r|capecitabine}}
{{r|capecitabine
{{r|azacitidine}}
{{r|azacitidine
{{r|decitabine}}
{{r|decitabine  


===Plant alkaloids and other natural products===
===Plant alkaloids and other natural products===
ATC/DDD group L01C.
==== Vinca alkaloids and analogues====
==== Vinca alkaloids and analogues====
{{r|Vinca alkaloid}}
{{r|Vinca alkaloid}}
{{r|Vincristine}}
{{r|Vincristine}}
{{r|Vinblastine}}
{{r|Vinblastine}}
{{r|Vindesine}}
{{r|Vinorelbine}}
ATC/DDD group L01CA.
ATC/DDD group L01CA.
====Podophyllotoxin derivatives====
====Podophyllotoxin derivatives====
{{r|Podophyllin}}
{{r|Etoposide}}
{{r|Teniposide}}


ATC/DDD group L01CB.
====Colchicine derivatives====
====Colchicine derivatives====
{{r|Colchicine}}
{{r|Colchicine}}
ATC/DDD group L01CC.
{{r|Demecolcine}}
 
====Taxanes====
====Taxanes====
{{r|Paclitaxel}}
{{r|Docetaxel}}
{{r|Paclitaxel poliglumex}}


ATC/DDD group L01CD.
====Other plant alkaloids and natural products====
====Other plant alkaloids and natural products====
{{r|Trabectedin}}


ATC/DDD group L01CX.
===Cytotoxic antibiotics and related substances===
===Cytotoxic antibiotics and related substances===
ATC/DDD group L01D.
====Actinomycines====
====Actinomycines====
 
{{r|Dactinomycin}}
ATC/DDD group L01DA.
====Anthracyclines and related substances====
====Anthracyclines and related substances====
 
{{r|Doxorubicin}}
ATC/DDD group L01DB.
{{r|Daunorubicin}}
{{r|Epirubicin}}
{{r|Aclarubicin}}
{{r|Zorubicin}}
{{r|Idarubicin}}
{{r|Mitoxantrone}}
{{r|Pirarubicin}}
{{r|Valrubicin}}
====Other cytotoxic antibiotics====
====Other cytotoxic antibiotics====
{{r|Bleomycin}}
{{r|Plicamycin}}
{{r|Mitomycin}}
{{r|Ixabepilone}}


ATC/DDD group L01DC.
===Other antineoplastic agents===
===Other antineoplastic agents===


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=====Anti-EpCAM=====
=====Anti-EpCAM=====
{{r|Edrecolomab}}is monclonal antibody against EpCAM (Entrez protein). Edrecolomab is a "anticolorectal carcinoma antibody for treatment of advanced colorectal carcinoma".[9]  
{{r|Edrecolomab}}is monclonal antibody against EpCAM (Entrez protein). Edrecolomab is a "anticolorectal carcinoma antibody for treatment of advanced colorectal carcinoma".[9]  
=====Anti-ERBB2====
=====Anti-ERBB2=====
{{r|Trastuzumab}}"HER2 (Entrez protein) antibody that lengthens remission time in metastatic breast cancer."
{{r|Trastuzumab}}"HER2 (Entrez protein) antibody that lengthens remission time in metastatic breast cancer."


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{{r|Gemtuzumab}}is an "anti-CD33 (Entrez protein) antibody calicheamicin conjugate".[13]  
{{r|Gemtuzumab}}is an "anti-CD33 (Entrez protein) antibody calicheamicin conjugate".[13]  


=====Anti-CD52======
=====Anti-CD52=====
    * Alemtuzumab is a "a therapeutic antibody directed against the CDw52 antigen (Entrez protein) expressed by the lymphocytes and has proven lytic abilities both in vitro and in vivo; has been sequenced".[14]
{{r|Alemtuzumab}}


=====Anti-VEGF=====
=====Anti-VEGF=====
{{r|Bevacizumab}}is an "anti-VEGF (Entrez protein) monoclonal antibody consisting of humanized murine antibody with antigen-binding, complementary-determining regions from murine VEGF".[15]  
{{r|Bevacizumab}}is an "anti-VEGF (Entrez protein) monoclonal antibody consisting of humanized murine antibody with antigen-binding, complementary-determining regions from murine VEGF".[15]


===Sensitizers used in photodynamic/radiation therapy===
===Sensitizers used in photodynamic/radiation therapy===
{{r|porfimer sodium}}
{{r|methyl aminolevulinate}}
{{r|aminolevulinic acid}}
{{r|temoporfin}}
{{r|efaproxiral}}


ATC/DDD group L01XD.
===[[Protein kinase]] inhibitors===
===Protein kinase inhibitors===
{{r|Imatinib}}
{{r|Gefitinib}}
{{r|Erlotinib}}
{{r|Sunitinib}}
{{r|Sorafenib}}
{{r|Dasatinib}}
{{r|Lapatinib}}
{{r|Nilotinib}}
{{r|Temsirolimus}}


ATC/DDD group L01XE
{{r|imatinib}}
{{r|gefitinib}}
{{r|erlotinib}}
{{r|sunitinib}}
{{r|sorafenib}}
{{r|dasatinib}}
{{r|lapatinib}}
{{r|nilotinib}}
{{r|temsirolimus}}
==Other related topics==
==Other related topics==
{{r|Antiemetic}}
{{r|Antiemetic}}
{{r|Protein kinase}}
==Articles related by keyphrases (Bot populated)==

Latest revision as of 11:00, 11 July 2024

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https://en.citizendium.org/wiki/index.php?title=Antineoplastic_agent/Related_Articles&printable=yes
A list of Citizendium articles, and planned articles, about Antineoplastic agent.
See also changes related to Antineoplastic agent, or pages that link to Antineoplastic agent or to this page or whose text contains "Antineoplastic agent".


Parent topics

  • Cancer [r]: A generic term for a large group of diseases that can affect any part of the body; one defining feature is the rapid creation of abnormal cells that grow beyond their usual boundaries, and which can then invade adjoining parts of the body and spread to other organs. [e]
  • Immunology [r]: The study of all aspects of the immune system in all animals. [e]
  • Oncology [r]: The medical diagnosis and treatment of neoplasia, using pharmacologic, radiation, immunologic and surgical techniques; relevant formal subspecialties are medical oncology in internal medicine and radiation oncology in radiology; surgeons also may specialize in neoplasia [e]

Subtopics

Alkylating agents

Nitrogen mustards

Alkyl sulfonates

Ethylene imines

Nitrosoureas

Epoxides

Other alkylating agents

Antimetabolites

Folic acid analogues

Purine analogues

Pyrimidine analogues

Plant alkaloids and other natural products

Vinca alkaloids and analogues

ATC/DDD group L01CA.

Podophyllotoxin derivatives

Colchicine derivatives

Taxanes

Other plant alkaloids and natural products

Cytotoxic antibiotics and related substances

Actinomycines

Anthracyclines and related substances

Other cytotoxic antibiotics

Other antineoplastic agents

ATC/DDD group L01X.

Platinum compounds

ATC/DDD group L01XA.

Methylhydrazines

ATC/DDD group L01XB.

Monoclonal antibodies

ATC/DDD group L01XC. Examples include:

Anti-EGRF
Anti-EpCAM
Anti-ERBB2
Anti-CD3 and anti-EpCAM
  • Catumaxomab [r]: Add brief definition or description Is a monoclonal antibody against CD3 (Entrez protein)and EpCAM (Entrez protein). "Extracorporeal PBMNC coating with catumaxomab may be an option to control intravascular cytokine release induced by therapeutic antibodies".[11]
Anti-MS4A1 (CD20 antigen)
Anti-SIGLEC3 (CD33)
Anti-CD52
Anti-VEGF

Sensitizers used in photodynamic/radiation therapy

Protein kinase inhibitors

Other related topics

Articles related by keyphrases (Bot populated)

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