Penciclovir/Related Articles: Difference between revisions

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imported>David E. Volk
(New page: {{subpages}} '''Penciclovir''' ('''PE2''') or '''penciclovirum''', is a guanosine analog, antiviral drug used to treat herpesviruses and is the active metabolite of the prodru...)
 
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'''Penciclovir''' ('''PE2''') or '''penciclovirum''', is a [[guanosine]] analog, [[antiviral drug]] used to treat [[herpesvirus]]es and is the active metabolite of the prodrug [[famciclovir]].  It is sold under the brand name '''Denavir®'''.  The longer [[half-life]] of penciclovir triphosphate in herpes-infected cells (10-20 hrs), compared to that of [[acyclovir]] (0,7 -1 hr), may be responsible for its ehanced results.
The triphosphate form competes with [[deoxyguanosine]] triphosphate for incorporation into viral DNA.  It only effects DNA synthesis of only those cells infected with [[herpes simplex virus]] (HSV).


==Parent topics==
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{{r|DNA synthesis}}
{{r|DNA synthesis}}
{{r|acyclovir}}
{{r|acyclovir}}
==Articles related by keyphrases (Bot populated)==
{{r|Family}}
{{r|Immunosuppressant}}
{{r|Herpes Simplex virus}}
{{r|Herpes Simplex Virus}}
{{r|Tributyl phosphate}}

Latest revision as of 11:01, 2 October 2024

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  • DNA synthesis [r]: Please do not use this term in your topic list, because there is no single article for it. Please substitute a more precise term. See DNA synthesis (disambiguation) for a list of available, more precise, topics. Please add a new usage if needed.
  • Acyclovir [r]: An antiviral, anti-metabolite drug, similar to guanine, that acts as a viral DNA chain terminator. [e]

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