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'''Skull stripping''' is a term used for processes in both [[neuroimaging]] and in [[anatomical]] [[dissection]]s. In neuroimaging, images are typically acquired [[in vivo]] or [[in situ]], i.e. with the [[brain]] inside the [[head]] of a living or dead subject. To analyze the brain separately, its share of the image has to be "peeled off" from the surrounding [[tissue]], mainly the [[skull]], [[skin]] and [[muscles]] of the head. This process is commonly referred to as '''skull stripping''' or '''brain extraction''' and represents an application of [[image segmentation]] techniques specifically to the [[vertebrate]] head. Both terms (and particularly the second) also have older uses, referring to the physical extraction of brain tissue from the head, as is common in anatomical dissections.
'''Skull stripping''' (also known as '''brain extraction''', '''brain peeling''' or '''head peeling''') is a term used to describe the separation of [[brain]] and non-brain [[tissue]] of the [[head]] of [[vertebrate]]s, and humans in particular.
 
While having its origins in [[anatomical]] [[dissection]]s (where ''brain extraction'' is more commonly used), the term is nowadays mostly employed to describe the application of [[image segmentation]] techniques to [[neuroimaging]] data of the vertebrate head. Such data are typically acquired [[in vivo]] or [[in situ]], i.e. with the [[brain]] inside the head of a living or dead subject. To analyze the brain separately (e.g. by means of [[brain morphometry]]), its share of the image has to be "peeled off" from the surrounding tissue — mainly the [[skull]], [[skin]] and [[muscles]] of the head — as well as [[cerebrospinal fluid]].
 
==Algorithms==
A common classification of skull stripping algorithms distinguishes between approaches based on [[mathematical morphology]] and [[thresholding]], on [[edge detection]], on [[a priori information]], or [[deformable-surface algorithm]]s. Various combinations thereof are also frequently employed.[[Category:Suggestion Bot Tag]]

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Skull stripping (also known as brain extraction, brain peeling or head peeling) is a term used to describe the separation of brain and non-brain tissue of the head of vertebrates, and humans in particular.

While having its origins in anatomical dissections (where brain extraction is more commonly used), the term is nowadays mostly employed to describe the application of image segmentation techniques to neuroimaging data of the vertebrate head. Such data are typically acquired in vivo or in situ, i.e. with the brain inside the head of a living or dead subject. To analyze the brain separately (e.g. by means of brain morphometry), its share of the image has to be "peeled off" from the surrounding tissue — mainly the skull, skin and muscles of the head — as well as cerebrospinal fluid.

Algorithms

A common classification of skull stripping algorithms distinguishes between approaches based on mathematical morphology and thresholding, on edge detection, on a priori information, or deformable-surface algorithms. Various combinations thereof are also frequently employed.