Tenofovir: Difference between revisions

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[[Image:Tenofovir structure.jpg|right|thumb|200px|{{#ifexist:Template:Tenofovir structure.jpg/credit|{{Tenofovir structure.jpg/credit}}<br/>|}}Tenofovir]]  
[[Image:Tenofovir structure.jpg|right|thumb|200px|{{#ifexist:Template:Tenofovir structure.jpg/credit|{{Tenofovir structure.jpg/credit}}<br/>|}}Tenofovir]]  
'''Tenofovir''' is a nucleotide analog [[reverse transcritase inhitor]] (nRTI) [[antiviral drug]] used to treat [[HIV]]/[[AIDS]] and is in clinical trials for treatment of [[hepatitis B]] infection.  The triphosphate from of the drug competes with the natural [[DNA]] [[nucleotide]] [[deoxyadenosine triphosphate]] (dATP) during DNA formation and it acts as a DNA chain terminator once incorporated because it lacks the normal [[deoxyribose]] sugar needed for connecting to the next DNA base.  
'''Tenofovir''' is a nucleotide analog [[reverse transcritase inhibitor]] (nRTI) [[antiviral drug]] used to treat [[HIV]]/[[AIDS]] and is in clinical trials for treatment of [[hepatitis B]] infection.  The triphosphate from of the drug competes with the natural [[DNA]] [[nucleotide]] [[deoxyadenosine triphosphate]] (dATP) during DNA formation and it acts as a DNA chain terminator once incorporated because it lacks the normal [[deoxyribose]] sugar needed for connecting to the next DNA base.  


== Synonyms and brand names ==
== Synonyms and brand names ==

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Tenofovir

Tenofovir is a nucleotide analog reverse transcritase inhibitor (nRTI) antiviral drug used to treat HIV/AIDS and is in clinical trials for treatment of hepatitis B infection. The triphosphate from of the drug competes with the natural DNA nucleotide deoxyadenosine triphosphate (dATP) during DNA formation and it acts as a DNA chain terminator once incorporated because it lacks the normal deoxyribose sugar needed for connecting to the next DNA base.

Synonyms and brand names

Synonyms

  • Tenofovir disoproxil
  • Tenofovir disoproxil fumarate
  • D,L-Tenofovir
  • TDF
  • PMPA

Brand Names

  • Apropovir
  • Viread

External links

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