Tumor necrosis factor-alpha: Difference between revisions

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==Tumor necrosis factor inhibitors==
==Tumor necrosis factor inhibitors==
* TNFR-Fc fusion protein (etanercept - pronounced et a ner' set) blocks the activity of TNF-alpha.<ref>{{MedMaster|Etanercept}}</ref>
* TNFR-Fc fusion protein (etanercept - pronounced et a ner' set) blocks the activity of TNF-alpha.<ref>{{MedMaster|Etanercept}}</ref>
* Infliximab is a chimeric monoclonal antibody that blocks the action of TNF-alpha by binding to it.<ref>{{MedMaster|Infliximab}}</ref>
* Infliximab (pronounced in flix' i mab)is a chimeric monoclonal antibody that blocks the action of TNF-alpha by binding to it.<ref>{{MedMaster|Infliximab}}</ref>


==References==
==References==
<references/>
<references/>

Revision as of 15:20, 1 September 2008

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In medicine, tumor necrosis factor-alpha is a "serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to tnf-beta (lymphotoxin), but they share TNF receptors.[1]

Tumor necrosis factor inhibitors

  • TNFR-Fc fusion protein (etanercept - pronounced et a ner' set) blocks the activity of TNF-alpha.[2]
  • Infliximab (pronounced in flix' i mab)is a chimeric monoclonal antibody that blocks the action of TNF-alpha by binding to it.[3]

References