Tumor necrosis factor-alpha: Difference between revisions

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(New page: {{subpages}} In medicine, '''tumor necrosis factor-alpha''' is a "serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes. It has necrotizing ac...)
 
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In [[medicine]], '''tumor necrosis factor-alpha''' is a "serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as '''tnf-alpha''', it is only 30% homologous to tnf-beta (lymphotoxin), but they share [[tumor necrosis factor receptor|tnf receptors]].<ref>{{MeSH}}</ref>
In [[medicine]], '''tumor necrosis factor-alpha''' is a "serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as '''TNF-alpha''', it is only 30% homologous to tnf-beta (lymphotoxin), but they share [[tumor necrosis factor receptor|TNF receptors]].<ref>{{MeSH}}</ref>
 
TNFR-Fc fusion protein (etanercept - pronounced et a ner' set) blocks the activity of TNF-alpha.<ref>{{MedMaster|Etanercept}}</ref>


==References==
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Revision as of 15:15, 1 September 2008

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In medicine, tumor necrosis factor-alpha is a "serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to tnf-beta (lymphotoxin), but they share TNF receptors.[1]

TNFR-Fc fusion protein (etanercept - pronounced et a ner' set) blocks the activity of TNF-alpha.[2]

References