Small bowel bacterial overgrowth
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Small bowel bacterial overgrowth is a syndrome of lower gastrointestinal symptoms that occurs in the settings such as gastrointestinal anatomic abnormalities (such as surgically created blind loops) or abnormal small intestinal motility (diabetic neuropathy).[1]
Small bowel bacterial overgrowth and Irritable bowel syndrome
More controversial is the connection between bacterial overgrowth and irritable bowel syndrome.[2] [3] Between 10% and 80% of patients with irritable bowel syndrome have bacterial overgrowth as detected by the lactulose H2 breath test.[2] However, the accuracy of the lactulose H2 breath test is disputed.[2]
Rifaximin, a nonabsorbed oral antibiotic improved some symptoms in a randomized controlled trial of patients with irritable bowel syndrome.[4]
References
- ↑ MedlinePlus Medical Encyclopedia: Small bowel bacterial overgrowth. Retrieved on 2008-01-04.
- ↑ 2.0 2.1 2.2 Drossman DA (2006). "Treatment for bacterial overgrowth in the irritable bowel syndrome". Ann. Intern. Med. 145 (8): 626–8. PMID 17043344. [e]
- ↑ Lin HC (2004). "Small intestinal bacterial overgrowth: a framework for understanding irritable bowel syndrome". JAMA 292 (7): 852–8. DOI:10.1001/jama.292.7.852. PMID 15316000. Research Blogging.
- ↑ Pimentel M, Park S, Mirocha J, Kane SV, Kong Y (2006). "The effect of a nonabsorbed oral antibiotic (rifaximin) on the symptoms of the irritable bowel syndrome: a randomized trial". Ann. Intern. Med. 145 (8): 557–63. PMID 17043337. [e]