User:Sekhar Talluri

1984: M.Sc. (Chemistry) from IIT, Delhi, India.

1993: Ph.D. from Cornell University. Thesis title: "NMR spectroscopic studies of protein unfolding." Thesis supervisor: Prof. Scheraga.

1993-1997: Research Fellow in Prof. Wagner's group in Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School.

1997-1998: Lecturer, MPR College, Visakahapatnam

1998-2006: Ad-hoc Lecturer, Assistant Professor, GITAM, Visakhapatnam, India.

2006-present: Associate Professor, Department of Biotechnology, GITAM University, India

Books

Coauthor for one Chapter entitled "Structural Bioinformatics" in book: Bioinformatics , Ukaaz Publishers

Publications

1. S. Talluri, G. T. Montelione, G. van Duyne, L. Piela, J. Clardy and H. A. Scheraga "Conformational properties of 2,4-Methanoproline in peptides: Evidence for 2,4-Methanopyrrolidine asymmetry based on solid-state X-ray crystallography, 1H-NMR in aqueous solution and CNDO/2 conformational energy calculations." Journal of the American Chemical Society, 109, 4473 (1987).

2. S. Talluri and H. A. Scheraga. "COSY with in-phase cross peaks" Journal of Magnetic Resonance, 86, 1 (1990).

3. S. Talluri and H. A. Scheraga "Amide H/D exchange in the thermal transition of bovine pancreatic Ribonuclease A" Biochemical and Biophysical Research Communications, 172, 800 (1990)

4. C. M. Falcomer, Y. C. Meinwald, I. Choudhary, S. Talluri, P.W.Millburn, J.C.Clardy and H. A. Scheraga "Chain reversals in model peptides: Studies of cystine-containing cyclic peptides. Conformational energies of cyclization of tetrapeptides of sequence Ac-Cys-Pro-X-Cys-NHMe." Journal of the American Chemical Society, 114, 4036 (1992).

5. S. Talluri, C. M. Falcomer and H. A. Scheraga "Energetic and structural basis for the preferential formation of the native disulfide loop involving Cys-65 and Cys-72 in synthetic fragments derived from the sequence of Ribonuclease A." Journal of the American Chemical Society, 115, 3041 (1993).

6. S. Talluri, D. M. Rothwarf and H. A. Scheraga. "Structural characterization of a three-disulfide intermediate of Ribonuclease A in both the folding and unfolding pathways." Biochemistry, 33, 10437 (1994).

7. S. Talluri and G. Wagner. "An optimized NOESY-HSQC" Journal of Magnetic Resonance, 112, 200 (1996). Citations(till 2006 in SCI)=109

8. S.Talluri, J.S.R.Murthy and A.Liwo. "Structural Bioinformatics" Chapter 4, pages 45-90, in Fundamentals of Bioinformatics. Edited by Irfan A. Khan & Atiya Khanum. Ukaaz publishers. (2002).

Courses taught: Biophysical techniques, Bioinformatics

My contributions

Biophysical techniques (1)  NMR spectroscopy

Stubs  Nuclear Overhauser effect  Chemical and magnetic equivalence  NMR instrumentation  Quantum fluids (def)  Quantum computing - (def)  Metabonomics (def)  Magnetogyric ratio (def)  Magnetically equivalent

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