Tranexamic acid

tranexamic acid
IUPAC name: 4-(aminomethyl)cyclohexane-1-carboxylic acid Synonyms: Formula: C8H15NO2
Uses:	antifibrinolytic
Properties:	pyrophoric Lewis acid
Hazards:	spontaneously ignites in air
Mass (g/mol): CAS #: 157.2102 1197-18-8

In medicine, tranexamic acid a hemostatic agent approved for hemorrhaging in hemophilia, with unapproved uses in cyanide poisioning, hereditary angioedema, hyperfibrinolysis induced hemorrhage, postsurgical hemorrhage and prevention of hemorrhage from cardiovascular instability after coronary artery bypass graft. It is an "inhibitor of plasminogen activation, and at much higher concentrations, a noncompetitive inhibitor of plasmin, i.e., actions similar to aminocaproic acid." It is similar to, but more potent than aminocaproic acid. It is also used to treat acquired angioedema due to deficiency of complement C1 inhibitor protein.

Synonyms and Trade Names

Synonyms tranexamsaeure tranhexamic acid trans AMCHA tranexmic acid trans-4-aminomethylcyclohexane-1-carboxylic acid trans-amcha trans-tranexamic acid

Brand Names Amcha® Amikapron® Amstat® Anvitoff® Carxamin® Cyclocapron® Cyklokapron® Emorhalt® Frenolyse® Mastop® Rikavarin® Rikavarin-S® Tamcha® Tranexan® Transamin® Trasamlon® Ugurol®

External links

The most up-to-date information about Tranexamic acid and other drugs can be found at the following sites.

• Tranexamic acid - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Tranexamic acid - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
• Tranexamic acid - Detailed information from DrugBank.