Proton pump inhibitor

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In medicine, proton pump inhibitors (PPI) are medications that "inhibit H(+)-K(+)-exchanging atpase. They are used as anti-ulcer agents and sometimes in place of histamine H2 antagonists for gastroesophageal reflux."[1]

Adverse effects

Proton pump inhibitors may be associated with spontaneous bacterial peritonitis.[2] These drugs may also be associated with pneumonia, Clostridium difficile diarrhea, and fractures.

References