CZ:Ref:DOI:10.1371/journal.pcbi.1000749

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Revision as of 14:13, 1 May 2010 by imported>Daniel Mietchen (slight expansion)
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Lefèvre J, Mangin JF (2010). "A reaction-diffusion model of human brain development". PLoS Comput Biol 6 (4): e1000749. DOI:10.1371/journal.pcbi.1000749. PMID 20421989. PMC PMC2858670. Research Blogging. [e]

Based on modeling gyrification as a reaction-diffusion process, the authors provide a mechanism — compatible with the sulcal roots hypothesis — by which the folding process of the cerebral cortex can be explained, along with its anatomical variability and common malformations like polymicrogyria and lissencephaly.
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