Coronary heart disease
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Cardiac computed tomographic angiography
Computed tomographic cardiac angiography (CT cardiac angiography) uses multidetector spiral computed tomography.[1][2][3] The physiologic significance of obstructions estimated to be 60% to 80% is difficult to predict.[4]
| Patients | Per patient | Per segment | |||
|---|---|---|---|---|---|
| Sensitivity | Specificity | Sensitivity | Specificity | ||
| CORE 64 study.[5] 2008 |
291 patients with suspected coronary heart disease and calcium scores ≤ 600 | 85% | 90% | 75% | 93% |
| Meijboom et al.[6] 2008 |
360 symptomatic patients | 99% | 64% | 88% | 90% |
| ACCURACY study.[7] 2008 |
230 symptomatic patients | 95% | 83% | 84% | 90% |
The accuracy using 64-row CT for detecting stenoses of 50% is:[8]
- sensitivity = 85%
- specificity = 90%
- ↑ Stein PD, Yaekoub AY, Matta F, Sostman HD (August 2008). "64-slice CT for diagnosis of coronary artery disease: a systematic review". The American journal of medicine 121 (8): 715–25. DOI:10.1016/j.amjmed.2008.02.039. PMID 18691486. Research Blogging.
- ↑ Mowatt G, Cook JA, Hillis GS, et al (July 2008). "64-slice computed tomography angiography in the diagnosis and assessment of coronary artery disease: systematic review and meta-analysis". Heart. DOI:10.1136/hrt.2008.145292. PMID 18669550. Research Blogging.
- ↑ Rubinshtein R, Halon DA, Gaspar T, et al (November 2007). "Impact of 64-slice cardiac computed tomographic angiography on clinical decision-making in emergency department patients with chest pain of possible myocardial ischemic origin". Am. J. Cardiol. 100 (10): 1522–6. DOI:10.1016/j.amjcard.2007.06.052. PMID 17996512. Research Blogging.
- ↑ Sato A, Hiroe M, Tamura M, et al (April 2008). "Quantitative measures of coronary stenosis severity by 64-Slice CT angiography and relation to physiologic significance of perfusion in nonobese patients: comparison with stress myocardial perfusion imaging". J. Nucl. Med. 49 (4): 564–72. DOI:10.2967/jnumed.107.042481. PMID 18344444. Research Blogging.
- ↑ 5.0 5.1 Miller, Julie M.; Carlos E. Rochitte, Marc Dewey, Armin Arbab-Zadeh, Hiroyuki Niinuma, Ilan Gottlieb, Narinder Paul, Melvin E. Clouse, Edward P. Shapiro, John Hoe, Albert C. Lardo, David E. Bush, Albert de Roos, Christopher Cox, Jeffery Brinker, Joao A.C. Lima (2008-11-27). "Diagnostic Performance of Coronary Angiography by 64-Row CT". N Engl J Med 359 (22): 2324-2336. DOI:10.1056/NEJMoa0806576. PMID 19038879. Retrieved on 2008-11-27. Research Blogging.
- ↑ 6.0 6.1 Meijboom WB, Meijs MF, Schuijf JD, et al. (December 2008). "Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study". J. Am. Coll. Cardiol. 52 (25): 2135–44. DOI:10.1016/j.jacc.2008.08.058. PMID 19095130. Research Blogging.
- ↑ 7.0 7.1 Budoff MJ, Dowe D, Jollis JG, et al. (November 2008). "Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial". J. Am. Coll. Cardiol. 52 (21): 1724–32. DOI:10.1016/j.jacc.2008.07.031. PMID 19007693. Research Blogging.
- ↑ Miller, Julie M.; Carlos E. Rochitte, Marc Dewey, Armin Arbab-Zadeh, Hiroyuki Niinuma, Ilan Gottlieb, Narinder Paul, Melvin E. Clouse, Edward P. Shapiro, John Hoe, Albert C. Lardo, David E. Bush, Albert de Roos, Christopher Cox, Jeffery Brinker, Joao A.C. Lima (2008-11-27). "Diagnostic Performance of Coronary Angiography by 64-Row CT". N Engl J Med 359 (22): 2324-2336. DOI:10.1056/NEJMoa0806576. Retrieved on 2008-11-27. Research Blogging.