G-protein-coupled receptor

In biology, G-protein-coupled receptors are the "largest family of cell surface receptors involved in signal transduction. They share a common structure and signal through heterotrimeric g-proteins."

Two principal signal transduction pathways involving the G-protein coupled receptors are proposed: the cyclic AMP signal pathway and the phosphatidylinositol signal pathway.

Examples of G-protein-coupled receptors include adrenergic receptors, angiotensin receptors, bradykinin receptors, CCR5 receptor (used by HIV to infect cells), and opioid receptors.