Finasteride

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Revision as of 12:05, 18 March 2010 by imported>Robert Badgett (New page: In medicine, '''finasteride''' (Proscar®) is "an orally active testosterone 5-alpha-reductase inhibitor. It is used as a surgical alternative for treatment of [[benign prostatic ...)
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In medicine, finasteride (Proscar®) is "an orally active testosterone 5-alpha-reductase inhibitor. It is used as a surgical alternative for treatment of benign prostatic hyperplasia."[1]

Finasteride has also been found to reduce the incidence of prostate cancer in the randomized controlled trial; however, the trial reported statistical significance in the increase in the risk of high grade prostate cancer.[2] Subsequent analysis of the data suggests the incidence of high grade cancer is increased but without statistical significance.[3]

External links

The most up-to-date information about Finasteride and other drugs can be found at the following sites.


References

  1. Anonymous (2024), Finasteride (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. Thompson IM, Goodman PJ, Tangen CM, Lucia MS, Miller GJ, Ford LG et al. (2003). "The influence of finasteride on the development of prostate cancer.". N Engl J Med 349 (3): 215-24. DOI:10.1056/NEJMoa030660. PMID 12824459. Research Blogging. Review in: J Fam Pract. 2003 Nov;52(11):833, 837
  3. Redman MW, Tangen CM, Goodman PJ, Lucia MS, Coltman CA, Thompson IM (2008). "Finasteride does not increase the risk of high-grade prostate cancer: a bias-adjusted modeling approach.". Cancer Prev Res (Phila Pa) 1 (3): 174-81. DOI:10.1158/1940-6207.CAPR-08-0092. PMID 19138953. Research Blogging.