Alcoholic hepatitis: Difference between revisions

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In [[medicine]], '''alcoholic hepatitis''' is "[[inflammation]] of the [[liver]] due to [[alcohol abuse]]. It is characterized by [[necrosis ]]of [[hepatocyte]]s, infiltration by [[neutrophil]]s, and deposit of mallory hyaline bodies. depending on its severity, the inflammatory lesion may be reversible or progress to [[liver cirrhosis]]."<ref>{{MeSH}}</ref><ref name="pmid19904248">{{cite journal| author=O'Shea RS, Dasarathy S, McCullough AJ| title=Alcoholic liver disease. | journal=Am J Gastroenterol | year= 2010 | volume= 105 | issue= 1 | pages= 14-32; quiz 33 | pmid=19904248  
In [[gastroenterology]], '''alcoholic hepatitis''' is "[[inflammation]] of the [[liver]] due to [[alcohol abuse]]. It is characterized by [[necrosis ]]of [[hepatocyte]]s, infiltration by [[neutrophil]]s, and deposit of mallory hyaline bodies. depending on its severity, the inflammatory lesion may be reversible or progress to [[liver cirrhosis]]."<ref>{{MeSH}}</ref><ref name="pmid19904248">{{cite journal| author=O'Shea RS, Dasarathy S, McCullough AJ| title=Alcoholic liver disease. | journal=Am J Gastroenterol | year= 2010 | volume= 105 | issue= 1 | pages= 14-32; quiz 33 | pmid=19904248  
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=19904248 | doi=10.1038/ajg.2009.593 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref>
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=19904248 | doi=10.1038/ajg.2009.593 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref>


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In gastroenterology, alcoholic hepatitis is "inflammation of the liver due to alcohol abuse. It is characterized by necrosis of hepatocytes, infiltration by neutrophils, and deposit of mallory hyaline bodies. depending on its severity, the inflammatory lesion may be reversible or progress to liver cirrhosis."[1][2]

Treatment

Corticosteroids may help in severe cases.[3]

The role of pentoxifylline is uncertain.[4]

References

  1. ↑ Anonymous (2024), Alcoholic hepatitis (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ↑ O'Shea RS, Dasarathy S, McCullough AJ (2010). "Alcoholic liver disease.". Am J Gastroenterol 105 (1): 14-32; quiz 33. DOI:10.1038/ajg.2009.593. PMID 19904248. Research Blogging.
  3. ↑ Rambaldi A, Saconato HH, Christensen E, Thorlund K, Wetterslev J, Gluud C (2008). "Systematic review: glucocorticosteroids for alcoholic hepatitis--a Cochrane Hepato-Biliary Group systematic review with meta-analyses and trial sequential analyses of randomized clinical trials.". Aliment Pharmacol Ther 27 (12): 1167-78. DOI:10.1111/j.1365-2036.2008.03685.x. PMID 18363896. Research Blogging.
  4. ↑ Whitfield K, Rambaldi A, Wetterslev J, Gluud C (2009). "Pentoxifylline for alcoholic hepatitis.". Cochrane Database Syst Rev (4): CD007339. DOI:10.1002/14651858.CD007339.pub2. PMID 19821406. Research Blogging.
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