Angiotensin II receptor antagonist: Difference between revisions
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imported>Louise Valmoria m ({{subpages}}) |
imported>Robert Badgett |
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==Adverse effects== | ==Adverse effects== | ||
Angiotensin II receptor antagonists can cause [[hyperkalemia]] | Angiotensin II receptor antagonists can cause [[hyperkalemia]]. The rise in potassium has been reported to be both similar to<ref> The ONTARGET Investigators. 2008. [http://content.nejm.org/cgi/content/full/358/15/1547 Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events]. N Engl J Med 358, no. 15:1547-1559. | ||
</ref> and less that occurs with [[angiotensin-converting enzyme inhibitors]].<ref name="pmid11044229">{{cite journal |author=Bakris GL, Siomos M, Richardson D, ''et al'' |title=ACE inhibition or angiotensin receptor blockade: impact on potassium in renal failure. VAL-K Study Group |journal=Kidney Int. |volume=58 |issue=5 |pages=2084–92 |year=2000 |pmid=11044229 |doi=10.1111/j.1523-1755.2000.00381.x}}</ref> | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 22:45, 17 April 2008
Mechanism of action
Angiotensin II receptor antagonists block angiotensin II AT1 receptors.
Adverse effects
Angiotensin II receptor antagonists can cause hyperkalemia. The rise in potassium has been reported to be both similar to[1] and less that occurs with angiotensin-converting enzyme inhibitors.[2]
References
- ↑ The ONTARGET Investigators. 2008. Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events. N Engl J Med 358, no. 15:1547-1559.
- ↑ Bakris GL, Siomos M, Richardson D, et al (2000). "ACE inhibition or angiotensin receptor blockade: impact on potassium in renal failure. VAL-K Study Group". Kidney Int. 58 (5): 2084–92. DOI:10.1111/j.1523-1755.2000.00381.x. PMID 11044229. Research Blogging.