Angiotensin II receptor antagonist

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Revision as of 22:45, 17 April 2008 by imported>Robert Badgett (→‎Adverse effects)
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Mechanism of action

Angiotensin II receptor antagonists block angiotensin II AT1 receptors.

Adverse effects

Angiotensin II receptor antagonists can cause hyperkalemia. The rise in potassium has been reported to be both similar to[1] and less that occurs with angiotensin-converting enzyme inhibitors.[2]

References

  1. The ONTARGET Investigators. 2008. Telmisartan, Ramipril, or Both in Patients at High Risk for Vascular Events. N Engl J Med 358, no. 15:1547-1559.
  2. Bakris GL, Siomos M, Richardson D, et al (2000). "ACE inhibition or angiotensin receptor blockade: impact on potassium in renal failure. VAL-K Study Group". Kidney Int. 58 (5): 2084–92. DOI:10.1111/j.1523-1755.2000.00381.x. PMID 11044229. Research Blogging.