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Typhus: A class of vector-borne diseases caused by Rickettsiae, usually presenting as acute febrile infections [e]
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Parent topics
- Vector-borne diseases [r]: Infectious diseases that do not transmit directly between their ultimate victims, but require an intermediate living carrier, such as mosquitoes in malaria or fleas in plague [e]
- Rickettsiae [r]: A tribe of gram-negative bacteria of the family rickettsiaceae, whose organisms are found in arthropods and are pathogenic for man and certain other vertebrate hosts [1] [e]
Subtopics
Diseases
- Epidemic typhus [r]: Most common and severe form of typhus, caused by louse-borne Rickettsia prowazekii [e]
- Endemic flea-borne typhus [r]: An infectious disease clinically similar to louse-borne epidemic typhus, but caused by Rickettsia typhi, which is transmitted from rat to man by the rat flea, Xenopsylla cheopis [e]
- Scrub typhus [r]: Add brief definition or description
- Brill-Zinsser disease [r]: A chronic form of epidemic typhus, in which disease may recur after a long dormant period [e]
Pathogens
- Rickettsia prowazekii [r]: Gram negative, obligate intracellular parasitic, aerobic bacteria that is the etiologic agent of epidemic typhus, transmitted in the faeces of lice. [e]
- Rickettsia typhi [r]: Add brief definition or description
- Orientia tsutsugamushi [r]: Add brief definition or description
Treatment
- Doxycycline [r]: Tetracycline derivative; treats malaria, anthrax, brucellosis, cholera, ornithosis, plague etc. [e]
- Chloramphenicol [r]: One of the first broad-spectrum antibiotics discovered; exceptionally wide spectrum but carries risk of fatal aplastic anemia [e]
- Azithromycin [r]: A macrolide type of antibiotic similar to erythromycin. [e]
- Rifampin [r]: Add brief definition or description}
- William Cullen [r]: (1710-1790) The leading British physician of the 18th century. [e]
- Nazi typhus and other vaccine experiments [r]: Conducted for the benefit of the German armed forces to test the effectiveness of vaccines against typhus, smallpox, cholera, and other diseases at Buchenwald Concentration Camp and Natzweiler Concentration Camp (December 1941 - February 1945} [e]
- ↑
This definition is at least in part based on: Anonymous (2023), Typhus (English). Medical Subject Headings. U.S. National Library of Medicine.