Zanamivir
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zanamivir | |||||||
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Uses: | influenza A & B | ||||||
Properties: | neuraminidase inhibitor | ||||||
Hazards: | see drug interactions | ||||||
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Zanamivir is a guanido-neuraminic acid that is a neuraminidase inhibitor used as an antiviral drug to treat influenza A and B.
Its IUPAC chemical name is (4S,5R,6R)-5-acetamido-4-(diaminomethylideneamino)-6-[(1R,2R)-1,2,3-trihydroxypropyl]-5,6-dihydro-4H-pyran-2-carboxylic acid and its chemical formula is C12H20N4O7.
Dosage
According to MedMaster, "the recommended dose of RELENZA for treatment of influenza in adults and pediatric patients ages 7 years of age and older is 10 mg twice daily (approximately 12 hours apart) for 5 days." Zanamivir is administered by inhalation and is supplied at 5 mg blister per dose so 20 blisters are needed. One Relenza Diskhaler contains 20 blisters.
Brand names
- GANA
- GNA
- Relenza (GlaxoSmithKline)
- ZMR
- Zanamavir
External links
The most up-to-date information about Zanamivir and other drugs can be found at the following sites.
- Zanamivir - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
- Zanamivir - Drug information for consumers from MedlinePlus (U.S. National Library of Medicine).
- Zanamivir - Detailed information from DrugBank.