Fludrocortisone: Difference between revisions
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imported>Robert Badgett (New page: Fludrocortisone has at least 50<ref name="pmid14356353">{{cite journal |author=Goldfien A, Laidlaw JC, Haydar NA, Renold AE, Thorn GW |title=Fluorohydrocortisone and chlorohydrocortisone, ...) |
imported>Meg Taylor (subpages) |
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Fludrocortisone has at least 50<ref name="pmid14356353">{{cite journal |author=Goldfien A, Laidlaw JC, Haydar NA, Renold AE, Thorn GW |title=Fluorohydrocortisone and chlorohydrocortisone, highly potent derivatives of compound F |journal=N. Engl. J. Med. |volume=252 |issue=11 |pages=415–21 |year=1955 |month=March |pmid=14356353 |doi= |url= |issn=}}</ref><ref name="pmid13268992">{{cite journal |author=Thorn GW, Renold AE, Morse WI, Goldfien A, Reddy WJ |title=Highly potent adrenal cortical steroids: structure and biologic activity |journal=Ann. Intern. Med. |volume=43 |issue=5 |pages=979–1000 |year=1955 |month=November |pmid=13268992 |doi= |url= |issn=}}</ref> times more mineralocorticoid activity than [[hydrocortisone]]. | Fludrocortisone has at least 50<ref name="pmid14356353">{{cite journal |author=Goldfien A, Laidlaw JC, Haydar NA, Renold AE, Thorn GW |title=Fluorohydrocortisone and chlorohydrocortisone, highly potent derivatives of compound F |journal=N. Engl. J. Med. |volume=252 |issue=11 |pages=415–21 |year=1955 |month=March |pmid=14356353 |doi= |url= |issn=}}</ref><ref name="pmid13268992">{{cite journal |author=Thorn GW, Renold AE, Morse WI, Goldfien A, Reddy WJ |title=Highly potent adrenal cortical steroids: structure and biologic activity |journal=Ann. Intern. Med. |volume=43 |issue=5 |pages=979–1000 |year=1955 |month=November |pmid=13268992 |doi= |url= |issn=}}</ref> times more mineralocorticoid activity than [[hydrocortisone]]. | ||
Revision as of 07:27, 30 September 2009
Fludrocortisone has at least 50[1][2] times more mineralocorticoid activity than hydrocortisone.
Fludrocortisone one mg orally per day is equivalent to aldosterone 4 mg intramuscularly every six hours.[3]
References
- ↑ Goldfien A, Laidlaw JC, Haydar NA, Renold AE, Thorn GW (March 1955). "Fluorohydrocortisone and chlorohydrocortisone, highly potent derivatives of compound F". N. Engl. J. Med. 252 (11): 415–21. PMID 14356353. [e]
- ↑ Thorn GW, Renold AE, Morse WI, Goldfien A, Reddy WJ (November 1955). "Highly potent adrenal cortical steroids: structure and biologic activity". Ann. Intern. Med. 43 (5): 979–1000. PMID 13268992. [e]
- ↑ Thorn GW, Sheppard RH, Morse WI, Reddy WJ, Beigelman PM, Renold AE (May 1955). "Comparative action of aldosterone and 9-alpha-fluorohydrocortisone in man". Ann. N. Y. Acad. Sci. 61 (2): 609–19. PMID 13249284. [e]