Trimethoprim/Definition: Difference between revisions

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imported>Howard C. Berkowitz
(New page: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to pyrimethamine. The interference with folic acid metabolism may cause a depression of [[hema...)
 
imported>Daniel Mietchen
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A [[pyrimidine]] inhibitor of [[dihydrofolate reductase]], it is an antibacterial related to [[pyrimethamine]]. The interference with folic acid metabolism may cause a depression of [[hematopoiesis]]. It is potentiated by [[sulfonamide]]s and the [[trimethoprim-sulfamethoxazole combination]] is the form most often used. It is sometimes used alone as an antimalarial. (Adapted from [[National Library of Medicine]]
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A [[pyrimidine]] inhibitor of [[dihydrofolate reductase]], it is an antibacterial related to [[pyrimethamine]]. The interference with folic acid metabolism may cause a depression of [[hematopoiesis]]. It is potentiated by [[sulfonamide]]s and the [[trimethoprim-sulfamethoxazole combination]] is the form most often used. It is sometimes used alone as an antimalarial.<noinclude>{{DefMeSH}}</noinclude>

Latest revision as of 16:53, 14 May 2010

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Trimethoprim [r]: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to pyrimethamine. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by sulfonamides and the trimethoprim-sulfamethoxazole combination is the form most often used. It is sometimes used alone as an antimalarial.

This definition is at least in part based on: Anonymous (2024), Trimethoprim (English). Medical Subject Headings. U.S. National Library of Medicine.