Aldosterone antagonist: Difference between revisions
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imported>Howard C. Berkowitz No edit summary |
imported>Robert Badgett No edit summary |
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* Canrenone | * Canrenone | ||
* Drospirenone | * Drospirenone | ||
* Eplerenone | * [[Eplerenone]] | ||
* [[Spironolactone]] | * [[Spironolactone]] | ||
| Line 12: | Line 12: | ||
* [[Chronic kidney disease]]<ref name="pmid19588415">{{cite journal| author=Navaneethan SD, Nigwekar SU, Sehgal AR, Strippoli GF| title=Aldosterone antagonists for preventing the progression of chronic kidney disease. | journal=Cochrane Database Syst Rev | year= 2009 | volume= | issue= 3 | pages= CD007004 | pmid=19588415 | * [[Chronic kidney disease]]<ref name="pmid19588415">{{cite journal| author=Navaneethan SD, Nigwekar SU, Sehgal AR, Strippoli GF| title=Aldosterone antagonists for preventing the progression of chronic kidney disease. | journal=Cochrane Database Syst Rev | year= 2009 | volume= | issue= 3 | pages= CD007004 | pmid=19588415 | ||
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=19588415 | doi=10.1002/14651858.CD007004.pub2 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref> | | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=19588415 | doi=10.1002/14651858.CD007004.pub2 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref> | ||
* [[Hirsutism]]<ref name="pmid19370553">{{cite journal| author=Brown J, Farquhar C, Lee O, Toomath R, Jepson RG| title=Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne. | journal=Cochrane Database Syst Rev | year= 2009 | volume= | issue= 2 | pages= CD000194 | pmid=19370553 | * [[Hirsutism]]<ref name="pmid19370553">{{cite journal| author=Brown J, Farquhar C, Lee O, Toomath R, Jepson RG| title=Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne. | journal=Cochrane Database Syst Rev | year= 2009 | volume= | issue= 2 | pages= CD000194 | pmid=19370553 | ||
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=19370553 | doi=10.1002/14651858.CD000194.pub2 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref> | | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=19370553 | doi=10.1002/14651858.CD000194.pub2 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref> | ||
* [[Hypertension]] | * [[Hypertension]] | ||
** Prevention of [[hypokalemia]] caused by [[diuretic#thiazides|thiazide]] [[diuretic]] therapy | ** Prevention of [[hypokalemia]] caused by [[diuretic#thiazides|thiazide]] [[diuretic]] therapy | ||
===Heart failure=== | |||
* [[Heart failure]] | |||
==Side effects== | ==Side effects== | ||
* [[Hyperkalemia]] | * [[Hyperkalemia]] | ||
Revision as of 10:17, 4 February 2011
In pharmacology, aldosterone antagonists are "compounds which inhibit or antagonize the biosynthesis or actions of aldosterone."[1] Their actions affect the larger renin-angiotensin system.
Examples include:
- Canrenone
- Drospirenone
- Eplerenone
- Spironolactone
Uses
- Ascites
- Chronic kidney disease[2]
- Hirsutism[3]
- Hypertension
- Prevention of hypokalemia caused by thiazide diuretic therapy
Heart failure
Side effects
References
- ↑ Anonymous (2024), Aldosterone antagonist (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Navaneethan SD, Nigwekar SU, Sehgal AR, Strippoli GF (2009). "Aldosterone antagonists for preventing the progression of chronic kidney disease.". Cochrane Database Syst Rev (3): CD007004. DOI:10.1002/14651858.CD007004.pub2. PMID 19588415. Research Blogging.
- ↑ Brown J, Farquhar C, Lee O, Toomath R, Jepson RG (2009). "Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne.". Cochrane Database Syst Rev (2): CD000194. DOI:10.1002/14651858.CD000194.pub2. PMID 19370553. Research Blogging.